CASPR2= Contactin-2 associated proteins- REFERRAL

Code:
CASPR2

Sample Type:

2mL Serum (Gel  5mL Yellow tube)

Ref Ranges/Units:

Units:  Negative/ Positive

Reference Range: Normal result=Negative

Turnaround:

3-4 Weeks

Frequency of Analysis:  Referred to RVI, Newcastle Hospitals, sent every day except Friday

Method:  Sent away to RVI, Newcastle Hospitals

Special Precautions/Comments:

Additional Information:

Indication: Found mostly in patients who have Morvan’s syndrome

Background:  CASPR2 is one of the VGKC-complex proteins. Antibodies to CASPR2 are found mostly in patients who have Morvans syndrome (Irani et al Brian 2010; Irani et al Ann Neurol 2012). They have also been found recently in some patients with cerebellar ataxia not necessarily with VGKC-complex precipitating antibodies (Becker at al JNNP 2012)

Interferences:  None known

References: Irani et a Becker at al JNNP 2012)  Brian 2010; Irani et al Ann Neurol 2012

See Also:  LGI1

Phone:  Gateshead Lab 0191 4456499 Option 4, Option 1

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