BCR-ABL ratio %
Code:
BCR-ABLR
Sample Type:
Purple top tube
Ref Ranges/Units:
N/A
Turnaround:
2 weeks
Special Precautions/Comments:
Additional Information:
Consultant Approved Referral Test:
Chronic myeloid leukemia (CML) is a hematopoietic disorder characterized by the malignant expansion of bone marrow stem cells, with the presence of a reciprocal translocation between chromosomes 9 and 22 resulting in the fusion gene, BCR-ABL, whose product is a 210-kd protein with tyrosine kinase activity.
The level of leukemic inhibition after treatment can be measured by quantitative real-time PCR (RT-PCR), which has become the main molecular technique used to monitor BCR-ABL transcript levels in CML during treatment with kinase inhibitors. Measuring the BCR-ABL ratio % can provide effective monitoring for response to treatment.
Consultant Approved Referral Test:
Chronic myeloid leukemia (CML) is a hematopoietic disorder characterized by the malignant expansion of bone marrow stem cells, with the presence of a reciprocal translocation between chromosomes 9 and 22 resulting in the fusion gene, BCR-ABL, whose product is a 210-kd protein with tyrosine kinase activity.
The level of leukemic inhibition after treatment can be measured by quantitative real-time PCR (RT-PCR), which has become the main molecular technique used to monitor BCR-ABL transcript levels in CML during treatment with kinase inhibitors. Measuring the BCR-ABL ratio % can provide effective monitoring for response to treatment.
Consultant Approved Referral Test:
Chronic myeloid leukemia (CML) is a hematopoietic disorder characterized by the malignant expansion of bone marrow stem cells, with the presence of a reciprocal translocation between chromosomes 9 and 22 resulting in the fusion gene, BCR-ABL, whose product is a 210-kd protein with tyrosine kinase activity.
The level of leukemic inhibition after treatment can be measured by quantitative real-time PCR (RT-PCR), which has become the main molecular technique used to monitor BCR-ABL transcript levels in CML during treatment with kinase inhibitors. Measuring the BCR-ABL ratio % can provide effective monitoring for response to treatment.
Consultant Approved Referral Test:
Chronic myeloid leukemia (CML) is a hematopoietic disorder characterized by the malignant expansion of bone marrow stem cells, with the presence of a reciprocal translocation between chromosomes 9 and 22 resulting in the fusion gene, BCR-ABL, whose product is a 210-kd protein with tyrosine kinase activity.
The level of leukemic inhibition after treatment can be measured by quantitative real-time PCR (RT-PCR), which has become the main molecular technique used to monitor BCR-ABL transcript levels in CML during treatment with kinase inhibitors. Measuring the BCR-ABL ratio % can provide effective monitoring for response to treatment.
Consultant Approved Referral Test:
Chronic myeloid leukemia (CML) is a hematopoietic disorder characterized by the malignant expansion of bone marrow stem cells, with the presence of a reciprocal translocation between chromosomes 9 and 22 resulting in the fusion gene, BCR-ABL, whose product is a 210-kd protein with tyrosine kinase activity.
The level of leukemic inhibition after treatment can be measured by quantitative real-time PCR (RT-PCR), which has become the main molecular technique used to monitor BCR-ABL transcript levels in CML during treatment with kinase inhibitors. Measuring the BCR-ABL ratio % can provide effective monitoring for response to treatment.
Consultant Approved Referral Test:
Chronic myeloid leukemia (CML) is a hematopoietic disorder characterized by the malignant expansion of bone marrow stem cells, with the presence of a reciprocal translocation between chromosomes 9 and 22 resulting in the fusion gene, BCR-ABL, whose product is a 210-kd protein with tyrosine kinase activity.
The level of leukemic inhibition after treatment can be measured by quantitative real-time PCR (RT-PCR), which has become the main molecular technique used to monitor BCR-ABL transcript levels in CML during treatment with kinase inhibitors. Measuring the BCR-ABL ratio % can provide effective monitoring for response to treatment.