Cyclosporin (ciclosporin)
Code:
CYC
Sample Type:
EDTA Whole Blood (Purple Top)
Minimum volume: 1 mL
Ref Ranges/Units:
Most individuals show an optimal response with a trough level of 100 – 400 ng/mL.
However, ranges vary depending on type of transplant and length post-transplant.
Turnaround:
Referral test – same/next day for urgent samples
Special Precautions/Comments:
Trough sample recommended (blood drawn immediately before scheduled dose).
Additional Information:
Cyclosporin is an immunosuppressant drug used to prevent rejection after solid organ transplantation. It has a narrow therapeutic window and is associated with many side effects. Therapeutic drug monitoring is therefore essential to optimise immunosuppression, minimise adverse effects and check patient compliance.