Special Precautions/Comments:

Additional Information:

The prothrombin gene G20210A mutation (also called Factor II mutation) is due to a single base pair substitution at nucleotide position 20210 , , resulting in an increased prothrombin level with increased risk for venous thrombosis because prothrombin is the precursor of thrombin (a serine protease and a key enzyme in the process of hemostasis) and thrombosis.