Mean Cell Volume (part of FBC profile)
Code:
MCV
Sample Type:
Purple top tube
Ref Ranges/Units:
Age related normal range (fl):
0 days: 95 - 121
7 days: 88 - 126
14 days: 86 - 124
1 month: 85 - 123
2 months: 77 - 115
3 months: 74 - 108
6 months: 70 - 86
2 years: 75 - 87
6 years: 77 - 87
12 years: Female 78 - 102 Male 78 - 98
18+ years: Female 80 - 102 Male 80 - 102
Age related normal range (fl):
0 days: 95 - 121
7 days: 88 - 126
14 days: 86 - 124
1 month: 85 - 123
2 months: 77 - 115
3 months: 74 - 108
6 months: 70 - 86
2 years: 75 - 87
6 years: 77 - 87
12 years: Female 78 - 102 Male 78 - 98
18+ years: Female 80 - 102 Male 80 - 102
Age related normal range (fl):
0 days: 95 - 121
7 days: 88 - 126
14 days: 86 - 124
1 month: 85 - 123
2 months: 77 - 115
3 months: 74 - 108
6 months: 70 - 86
2 years: 75 - 87
6 years: 77 - 87
12 years: Female 78 - 102 Male 78 - 98
18+ years: Female 80 - 102 Male 80 - 102
Age related normal range (fl):
0 days: 95 - 121
7 days: 88 - 126
14 days: 86 - 124
1 month: 85 - 123
2 months: 77 - 115
3 months: 74 - 108
6 months: 70 - 86
2 years: 75 - 87
6 years: 77 - 87
12 years: Female 78 - 102 Male 78 - 98
18+ years: Female 80 - 102 Male 80 - 102
Age related normal range (fl):
0 days: 95 - 121
7 days: 88 - 126
14 days: 86 - 124
1 month: 85 - 123
2 months: 77 - 115
3 months: 74 - 108
6 months: 70 - 86
2 years: 75 - 87
6 years: 77 - 87
12 years: Female 78 - 102 Male 78 - 98
18+ years: Female 80 - 102 Male 80 - 102
Turnaround:
Urgent requests < 90 mins Routine requests < 4hours
Special Precautions/Comments:
Additional Information:
Mean cell volume provides a measurement of the average size of the red cells (erythrocytes) in the blood, providing an indication of whether the red cells are smaller (microcytic), normal (normocytic) or larger (macrocytic).
Mean cell volume provides a useful indicator of microcytic, hypochromic and macrocytic anaemias when used with other red cell indices of the full blood count profile, including Mean Cell Haemoglobin (MCH), and Mean Cell Haemoglobin Concentration (MCHC).
The common causes of microcytic and hypochromic anaemia (decreased MCV and MCH) are as follows:
• Iron deficiency anaemia
• Anaemia of chronic disease
• Thalassemia
• Sideroblastic anaemia
The common causes of macrocytic anaemia (increased MCV) are as follows:
• Folate deficiency anaemia
• Vitamin B12 deficiency anaemia
• Liver disease
• Haemolytic anaemias
• Hypothyroidism
• Excessive alcohol intake
• Aplastic anaemia
• Myelodysplastic syndrome
The common causes of normocytic and normochromic anaemia (normal MCV) are as follows:
• Anaemia of chronic disease
• Acute blood loss
• Haemolytic anaemia, such as autoimmune haemolytic anaemia, hereditary spherocytosis, or non-spherocytic congenital haemolytic anaemia (G6PD deficiency, other)
• Anaemia of renal disease
• Aplastic anaemia
Mean cell volume provides a measurement of the average size of the red cells (erythrocytes) in the blood, providing an indication of whether the red cells are smaller (microcytic), normal (normocytic) or larger (macrocytic).
Mean cell volume provides a useful indicator of microcytic, hypochromic and macrocytic anaemias when used with other red cell indices of the full blood count profile, including Mean Cell Haemoglobin (MCH), and Mean Cell Haemoglobin Concentration (MCHC).
The common causes of microcytic and hypochromic anaemia (decreased MCV and MCH) are as follows:
• Iron deficiency anaemia
• Anaemia of chronic disease
• Thalassemia
• Sideroblastic anaemia
The common causes of macrocytic anaemia (increased MCV) are as follows:
• Folate deficiency anaemia
• Vitamin B12 deficiency anaemia
• Liver disease
• Haemolytic anaemias
• Hypothyroidism
• Excessive alcohol intake
• Aplastic anaemia
• Myelodysplastic syndrome
The common causes of normocytic and normochromic anaemia (normal MCV) are as follows:
• Anaemia of chronic disease
• Acute blood loss
• Haemolytic anaemia, such as autoimmune haemolytic anaemia, hereditary spherocytosis, or non-spherocytic congenital haemolytic anaemia (G6PD deficiency, other)
• Anaemia of renal disease
• Aplastic anaemia
Mean cell volume provides a measurement of the average size of the red cells (erythrocytes) in the blood, providing an indication of whether the red cells are smaller (microcytic), normal (normocytic) or larger (macrocytic).
Mean cell volume provides a useful indicator of microcytic, hypochromic and macrocytic anaemias when used with other red cell indices of the full blood count profile, including Mean Cell Haemoglobin (MCH), and Mean Cell Haemoglobin Concentration (MCHC).
The common causes of microcytic and hypochromic anaemia (decreased MCV and MCH) are as follows:
• Iron deficiency anaemia
• Anaemia of chronic disease
• Thalassemia
• Sideroblastic anaemia
The common causes of macrocytic anaemia (increased MCV) are as follows:
• Folate deficiency anaemia
• Vitamin B12 deficiency anaemia
• Liver disease
• Haemolytic anaemias
• Hypothyroidism
• Excessive alcohol intake
• Aplastic anaemia
• Myelodysplastic syndrome
The common causes of normocytic and normochromic anaemia (normal MCV) are as follows:
• Anaemia of chronic disease
• Acute blood loss
• Haemolytic anaemia, such as autoimmune haemolytic anaemia, hereditary spherocytosis, or non-spherocytic congenital haemolytic anaemia (G6PD deficiency, other)
• Anaemia of renal disease
• Aplastic anaemia
Mean cell volume provides a measurement of the average size of the red cells (erythrocytes) in the blood, providing an indication of whether the red cells are smaller (microcytic), normal (normocytic) or larger (macrocytic).
Mean cell volume provides a useful indicator of microcytic, hypochromic and macrocytic anaemias when used with other red cell indices of the full blood count profile, including Mean Cell Haemoglobin (MCH), and Mean Cell Haemoglobin Concentration (MCHC).
The common causes of microcytic and hypochromic anaemia (decreased MCV and MCH) are as follows:
• Iron deficiency anaemia
• Anaemia of chronic disease
• Thalassemia
• Sideroblastic anaemia
The common causes of macrocytic anaemia (increased MCV) are as follows:
• Folate deficiency anaemia
• Vitamin B12 deficiency anaemia
• Liver disease
• Haemolytic anaemias
• Hypothyroidism
• Excessive alcohol intake
• Aplastic anaemia
• Myelodysplastic syndrome
The common causes of normocytic and normochromic anaemia (normal MCV) are as follows:
• Anaemia of chronic disease
• Acute blood loss
• Haemolytic anaemia, such as autoimmune haemolytic anaemia, hereditary spherocytosis, or non-spherocytic congenital haemolytic anaemia (G6PD deficiency, other)
• Anaemia of renal disease
• Aplastic anaemia
Mean cell volume provides a measurement of the average size of the red cells (erythrocytes) in the blood, providing an indication of whether the red cells are smaller (microcytic), normal (normocytic) or larger (macrocytic).
Mean cell volume provides a useful indicator of microcytic, hypochromic and macrocytic anaemias when used with other red cell indices of the full blood count profile, including Mean Cell Haemoglobin (MCH), and Mean Cell Haemoglobin Concentration (MCHC).
The common causes of microcytic and hypochromic anaemia (decreased MCV and MCH) are as follows:
• Iron deficiency anaemia
• Anaemia of chronic disease
• Thalassemia
• Sideroblastic anaemia
The common causes of macrocytic anaemia (increased MCV) are as follows:
• Folate deficiency anaemia
• Vitamin B12 deficiency anaemia
• Liver disease
• Haemolytic anaemias
• Hypothyroidism
• Excessive alcohol intake
• Aplastic anaemia
• Myelodysplastic syndrome
The common causes of normocytic and normochromic anaemia (normal MCV) are as follows:
• Anaemia of chronic disease
• Acute blood loss
• Haemolytic anaemia, such as autoimmune haemolytic anaemia, hereditary spherocytosis, or non-spherocytic congenital haemolytic anaemia (G6PD deficiency, other)
• Anaemia of renal disease
• Aplastic anaemia
South of Tyne & Wear Pathology Centre
