Nucleated Red Blood Cells (part of FBC profile)
Code:
NRBC
Sample Type:
Purple top tube
Ref Ranges/Units:
0
Turnaround:
Urgent requests < 90 mins Routine requests < 4hours
Special Precautions/Comments:
Additional Information:
Nucleated red blood cells (NRBCs) are immature red blood cells not normally seen in the peripheral blood beyond the neonatal period. NRBCs provide a measure of erythropoietic activity. Increased NRBCs can occur during acute haemolytic episodes and severe hypoxic stress, or as a result of a haematological malignancy. This includes many leukaemias and myelodysplastic syndromes, and some kinds of lymphoma.
NRBC can also be present in thalassaemia syndromes, bone marrow metastases of solid tumours, extramedullary haematopoiesis and other conditions of haematopoietic stress such as sepsis, or massive haemorrhages.Nucleated red blood cells (NRBCs) are immature red blood cells not normally seen in the peripheral blood beyond the neonatal period. NRBCs provide a measure of erythropoietic activity. Increased NRBCs can occur during acute haemolytic episodes and severe hypoxic stress, or as a result of a haematological malignancy. This includes many leukaemias and myelodysplastic syndromes, and some kinds of lymphoma.
NRBC can also be present in thalassaemia syndromes, bone marrow metastases of solid tumours, extramedullary haematopoiesis and other conditions of haematopoietic stress such as sepsis, or massive haemorrhages.Nucleated red blood cells (NRBCs) are immature red blood cells not normally seen in the peripheral blood beyond the neonatal period. NRBCs provide a measure of erythropoietic activity. Increased NRBCs can occur during acute haemolytic episodes and severe hypoxic stress, or as a result of a haematological malignancy. This includes many leukaemias and myelodysplastic syndromes, and some kinds of lymphoma.
NRBC can also be present in thalassaemia syndromes, bone marrow metastases of solid tumours, extramedullary haematopoiesis and other conditions of haematopoietic stress such as sepsis, or massive haemorrhages.Nucleated red blood cells (NRBCs) are immature red blood cells not normally seen in the peripheral blood beyond the neonatal period. NRBCs provide a measure of erythropoietic activity. Increased NRBCs can occur during acute haemolytic episodes and severe hypoxic stress, or as a result of a haematological malignancy. This includes many leukaemias and myelodysplastic syndromes, and some kinds of lymphoma.
NRBC can also be present in thalassaemia syndromes, bone marrow metastases of solid tumours, extramedullary haematopoiesis and other conditions of haematopoietic stress such as sepsis, or massive haemorrhages.