Troponin-T
Code:
TROP-T
Sample Type:
Serum (Gold Top)
Minimum volume: 1 mL
Ref Ranges/Units:
<14 ng/L
Results >14 ng/L from primary care and ≥52 ng/L from A&E will be urgently phoned.
Turnaround:
Same Day (60 minutes from receipt for Urgent Samples)
Stability:
Stable for 24 hours at 2‐8°C
12 months at ‐20°C
Freeze only once
Special Precautions/Comments:
Additional Information:
Troponins are proteins that form a complex which control the interaction of actin and myosin to regulate contraction in striated muscle. Skeletal and cardiac isoforms are distinct from each other. Therefore, the cardiac isoform of Troponin-T is a specific marker of cardiac damage which is used in investigation of acute myocardial infarction (MI), particularly in non-ST elevation MI (NSTEMI). A rise or fall in troponin-T levels may indicate cardiac damage, although it is not specific for MI. Troponin levels may remain elevated for 2 weeks after an MI.
The laboratory uses the Roche high sensitivity troponin-T method (hs-cTnT) which can detect changes 1 hour post MI. Measurement of troponin-T should be based upon local trust guidelines and protocols.
South of Tyne & Wear Pathology Centre
