Urine Protein Electrophoresis (Bence Jones protein)
Code:
UBJP
Sample Type:
Random urine – plain, no preservative
Early morning sample is preferred.
Boric acid specimens are unacceptable.
Ref Ranges/Units:
Interpretation provided.
Any new urine Bence Jones Protein detected is urgently communicated as per North East and North Cumbria Immunology Speciality Reference Group (NENC-SRG-Immunology) v1.3.
Turnaround:
Within 2 weeks
Special Precautions/Comments:
Please send a urine and a serum sample for electrophoresis for a complete myeloma screen.
Additional Information:
The presence of a significant amounts of free light chains in the urine (known as Bence Jones protein) may indicate a B cell lymphoproliferative disease such as multiple myeloma. Urine protein electrophoresis is used in conjunction with serum protein electrophoresis to screen for myeloma. Serum free light chains (SFLC) is an alternative method which can be used to investigate and quantify any free light chains in the serum. Presence of an intact monoclonal protein may indicate renal impairment.
South of Tyne & Wear Pathology Centre
